Article
Expression of adenylyl cyclase types III and VI in human hyperfunctioning thyroid nodules.
Molecular and cellular endocrinology - 30 May 2003
Celano M, Arturi F, Presta I, Bruno R, Scarpelli D, Calvagno M G, Cristofaro C, Bulotta S, Giannasio P, Sacco R, Filetti S, Russo D
Abstract excerpt
Hyperfunctioning thyroid nodules are characterized by the presence of spontaneous somatic mutations responsible for constitutive activation of the cAMP pathway. However, alterations affecting other elements of the cAMP signaling system may counteract the effects of the mutations. In this study, the expression of the adenylyl cyclase (AC) types III and VI was investigated by Western blot in 18 hyperfunctioning...
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