Article
Variability of the human aryl hydrocarbon receptor nuclear translocator (ARNT) gene.
Journal of human genetics - 1 Jan 2002
Scheel Julia, Hussong Ragna, Schrenk Dieter, Schmitz Hans-Joachim
Abstract excerpt
The aryl hydrocarbon receptor nuclear translocator (ARNT) plays an essential role in vertebrate transcriptional regulation as the common subunit of transcriptionally active complexes like the aryl hydrocarbon receptor (AHR)/ARNT heterodimer and hypoxia-inducible factor 1, mediating cellular responses to certain xenobiotics and to hypoxia, respectively. A cohort of healthy Caucasian volunteers was screened for...
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