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Article

MOZ fusion proteins in acute myeloid leukaemia

1 Jan 2006

Abstract excerpt

MOZ (monocytic leukaemia zinc finger protein; also known as ZNF220 or MYST3) is a member of the MYST family of protein acetyltransferases. Chromosomal translocations involving the MOZ gene are associated with AML (acute myeloid leukaemia), suggesting that it has a role in haematopoiesis. Recurrent reciprocal translocations fuse the MOZ gene [or the gene encoding MORF (MOZ-related factor); also known as MYST4] to...

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PMID: 16626284
DOI: 10.1042/bss0730023

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