Article
Genomic cloning and promoter analysis of macrophage inflammatory protein (MIP)-2, MIP-1 alpha, and MIP-1 beta, members of the chemokine superfamily of proinflammatory cytokines.
Journal of immunology (Baltimore, Md. : 1950) - 1 Jun 1993
Widmer U, Manogue K R, Cerami A, Sherry B
Abstract excerpt
Macrophage inflammatory protein (MIP)-2, MIP-1 alpha, and MIP-1 beta all belong to the newly recognized "chemokine" superfamily of structurally related, activation-inducible cytokines with inflammatory and growth regulatory activities. We report the isolation and sequencing of genomic clones for...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Chemokine CCL4
- Chemokine CXCL2
- Cloning, Molecular
- Cytokines
- Growth Substances
- Humans
- Inflammation
- Macrophage Inflammatory Proteins
- Mice
- Molecular Sequence Data
- Monokines
- Mutation
- Promoter Regions, Genetic
- Sequence Homology, Nucleic Acid