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Article

Specific inhibition of bovine viral diarrhea virus replicase.

Journal of virology - 1 Jun 2003

Sun Jin-Hua, Lemm Julie A, O'Boyle Donald R, Racela Jason, Colonno Richard, Gao Min

Abstract excerpt

Compound-1453 was identified and characterized as a specific inhibitor of bovine viral diarrhea virus (BVDV). The concentration of compound-1453 which results in 50% protection from virus-induced cytopathic effect is approximately 2.2 microM, with a therapeutic index of 60, and it is not active against a panel of RNA and DNA viruses. A time-of-addition experiment suggested that compound-1453 targets a stage of...

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Source

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Identifiers

PMID: 12767995
DOI: 10.1128/jvi.77.12.6753-6760.2003
PMCID: PMC156199

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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