Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional Characterization of Bovine Viral Diarrhea Virus Nonstructural Protein 5A by Reverse Genetic Analysis and Live Cell Imaging

17 Oct 2013

Abstract excerpt

Nonstructural protein 5A (NS5A) of bovine viral diarrhea virus (BVDV) is a hydrophilic phosphoprotein with RNA binding activity and a critical component of the viral replicase. In silico analysis suggests that NS5A encompasses three domains interconnected by two low-complexity sequences (LCSs). While domain I harbors two functional determinants, an N-terminal amphipathic helix important for membrane association,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animal Disease Management and Epidemiology
Share to Animal Virus Infections Studies
Share to Viral gastroenteritis research and epidemiology

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24131714
DOI: 10.1128/jvi.01957-13

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 25 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional Characterization of Bovine Viral Diarrhea Virus Nonstructural Protein 5A by Reverse Genetic Analysis and Live Cell ImagingPMID 24131714Read ↗

Molecular biology of bovine viral diarrhea virus.Semantic proximity Read ↗

Bovine viral diarrhea virus NS4B protein is an integral membrane protein associated with Golgi markers and rearranged host membranesSemantic proximity Read ↗

Insights into the secondary and tertiary structure of the Bovine Viral Diarrhea Virus Internal Ribosome Entry SiteSemantic proximity Read ↗

Packaging defects in pestiviral NS4A can be compensated by mutations in NS2 and NS3.Semantic proximity Read ↗

Complex signals in the genomic 3′ nontranslated region of bovine viral diarrhea virus coordinate translation and replication of the viral RNASemantic proximity Read ↗

Hepatitis C virus and the related bovine viral diarrhea virus considerably differ in the functional organization of the 5' non-translated region: implications for the viral life cycle.Semantic proximity Read ↗

Mutations in the 5' nontranslated region of bovine viral diarrhea virus result in altered growth characteristics.Semantic proximity Read ↗

RNA-Seq based transcriptome analysis during bovine viral diarrhoea virus (BVDV) infectionSemantic proximity Read ↗

Construction and characterization of a reverse genetics system of bovine parainfluenza virus type 3c as a tool for rapid screening of antivirals in vitroSemantic proximity Read ↗

Genetic analysis of the pestivirus nonstructural coding region: defects in the NS5A unit can be complemented in trans.Semantic proximity Read ↗

The NS5A protein of bovine viral diarrhoea virus interacts with the α subunit of translation elongation factor-1Semantic proximity Read ↗

Essential and nonessential elements in the 3' nontranslated region of Bovine viral diarrhea virus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.