Article
Suppression of bovine viral diarrhea virus replication by single and dual short hairpin RNA-mediated RNA interference.
Research in veterinary science - 1 Aug 2012
Ni Wei, Hu Shengwei, Qiao Jun, Yu Yuan, Wang Dawei, Tong Qi, Zhang Yong, Chen Chuangfu
Abstract excerpt
Bovine viral diarrhea virus (BVDV) is one of the most important pathogens to the cattle industry, causing a significant economic loss throughout the world. Despite the wide use of various control measures for BVDV, the disease remains prevalent. In this study, we achieved an efficient inhibition of NADL strain replication by plasmid-mediated shRNA targeting conserved regions of the viral genome. To further...
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