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Article

Malignant transformation of thyroid follicular cells by galectin-3.

Cancer letters - 30 May 2003

Takenaka Yukinori, Inohara Hidenori, Yoshii Tadashi, Oshima Kazuo, Nakahara Susumu, Akahani Shiro, Honjo Yuichiro, Yamamoto Yoshifumi, Raz Avraham, Kubo Takeshi

Abstract excerpt

Galectin-3, a beta-galactoside binding lectin, is highly expressed in thyroid carcinomas of follicular cell origin, whereas neither benign thyroid adenomas nor normal thyroid tissues express galectin-3. We previously showed that antisense inhibition of galectin-3 expression markedly reduced the malignant phenotype of thyroid papillary carcinoma cells. In the present study we transfected galectin-3 cDNA into TAD-2...

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Identifiers

PMID: 12767519
DOI: 10.1016/s0304-3835(03)00056-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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