Article
Phenotypic changes of the thyrocyte membrane in papillary thyroid carcinoma. A three-dimensional study.
Journal of endocrinological investigation - 1 Mar 2011
Crescenzi A, Taccogna S, Turrini L, Cicciarella Modica D, Papini E, Gallo A, Guidobaldi L, Zelano G, Giannakakis C, Nardi F
Abstract excerpt
Aim of the study was to assess the presence of structural changes in the complex carbohydrate chains of thyroid epithelia undergoing neoplastic transformation. We investigated thyroid cells from neoplastic lesions using a panel of lectins with specific affinity for distinct carbohydrate residues. Sixty samples of thyroid tissue, including normal, hyperplastic and neoplastic lesions were obtained from surgical...
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