Article
[Polymorphism on codon 98 of the galectin-3 gene is not associated to benign and malignant thyroid tumors].
Arquivos brasileiros de endocrinologia e metabologia - 1 Dec 2006
Martins Luciane, Leoni Suzana Garcia, Friguglietti Celso U M, Ward Laura Sterian, Kulcsar Marco Aurélio V, Kimura Edna Teruko
Abstract excerpt
Galectin-3 is a multifunctional protein highly expressed in thyroid cancer. The galectin-3 gene (LGALS3) has several annotated candidates SNPs, however the relationship between galectin-3 SNPs and specific phenotypic variations relevant to health has not been evaluated. In this study, we investigated SNPs in the galectin-3 gene and a putative association with thyroid tumorigenesis. The presence of LGALS3 SNPs in...
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