Article
Effects of various CYP2D6 genotypes on the steady-state plasma concentrations of risperidone and its active metabolite, 9-hydroxyrisperidone, in Japanese patients with schizophrenia.
Therapeutic drug monitoring - 1 Jun 2003
Mihara Kazuo, Kondo Tsuyoshi, Yasui-Furukori Norio, Suzuki Akihito, Ishida Masayuki, Ono Shingo, Kubota Takahiro, Iga Tatsuji, Takarada Yutaka, de Vries Ronald, Kaneko Sunao
Abstract excerpt
The effects of various CYP2D6 genotypes on the steady-state plasma concentrations (Css) of risperidone and its active metabolite, 9-hydroxyrisperidone, were studied in 85 Japanese schizophrenic patients (27 men and 58 women) treated with 6 mg/d risperidone for at least 2 weeks. Plasma concentrati...
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