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Article

Effects of CYP2D6 and CYP3A5 genotypes on the plasma concentrations of risperidone and 9-hydroxyrisperidone in Korean schizophrenic patients.

Journal of clinical psychopharmacology - 1 Jun 2009

Kang Rhee-Hun, Jung Sun-Min, Kim Kyoung-Ah, Lee Duk-Ki, Cho Hyun-Kee, Jung Bong-Joo, Kim Young-Ku, Kim Seung-Hyun, Han Changsu, Lee Min-Soo, Park Ji-Young

Abstract excerpt

This study was conducted to evaluate the effects of the CYP2D6 and CYP3A5 genotypes on the steady-state plasma levels of risperidone (RIS), 9-hydroxyrisperidone (9-OH-RIS), and the active moiety (RIS plus 9-OH-RIS) in Korean schizophrenic patients. Sixty-four Korean schizophrenic patients were enrolled. CYP2D6 and CYP3A5 genotypes were determined, and the plasma levels of RIS and 9-OH-RIS were measured using...

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PMID: 19440082
DOI: 10.1097/JCP.0b013e3181a289e0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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