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Article

Mechanisms of resistance to TRAIL-induced apoptosis in cancer.

Cancer gene therapy - 1 Mar 2005

Zhang Lidong, Fang Bingliang

Abstract excerpt

The tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is regarded as a potential anticancer agent. However, considerable numbers of cancer cells, especially some highly malignant tumors, are resistant to apoptosis induction by TRAIL, and some cancer cells that were originally sensitive to TRAIL-induced apoptosis can become resistant after repeated exposure (acquired resistance). Understanding the...

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PMID: 15550937
DOI: 10.1038/sj.cgt.7700792

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FADD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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