Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of an IL-10 polymorphism in idiopathic pulmonary fibrosis.

Genes and immunity - 1 Jun 2003

Whittington H A, Freeburn R W, Godinho S I H, Egan J, Haider Y, Millar A B

Abstract excerpt

Idiopathic pulmonary fibrosis (IPF) is a chronic progressive fibrotic disorder of the lung parenchyma. We have demonstrated changes in IL-10 protein production by alveolar macrophages (AMs) from patients with IPF, which we hypothesise could be because of an IL-10 gene polymorphism. We have screened the coding sequence and 3' untranslated region of IL-10 for polymorphisms using single-standard conformational...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Aged, 80 and over
Share to Chlorocebus aethiops

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to COS Cells

Share to Interleukin-10

Share to Mutation

Share to Polymorphism, Single-Stranded Conformational

Share to Pulmonary Fibrosis

Source

Identifiers

PMID: 12761561
DOI: 10.1038/sj.gene.6363959

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Analysis of an IL-10 polymorphism in idiopathic pulmonary fibrosis.PMID 12761561Read ↗

Analysis of gene polymorphisms in interleukin-10 and transforming growth factor-beta 1 in sarcoidosis.Semantic proximity Read ↗

A Gly15Arg mutation in the interleukin-10 gene reduces secretion of interleukin-10 in Crohn disease.Semantic proximity Read ↗

An intracytoplasmic IL-10 receptor variant permits rapid reduction in STAT3 activation.Semantic proximity Read ↗

Results of Frequency Analysis Distribution of Polymorphism Rs1800895 592C>A In IL10 Gene among Patients with Chronic Polypoid RhinosinusitisSemantic proximity Read ↗

A MnlI restriction site polymorphism in the interleukin-10 gene promoter.Semantic proximity Read ↗

Role of Stat3 in Lipopolysaccharide-Induced IL-10 Gene ExpressionSemantic proximity Read ↗

Transforming growth factor-beta1 gene polymorphisms are associated with disease progression in idiopathic pulmonary fibrosis.Semantic proximity Read ↗

Novel variants of the IL-10 receptor 1 affect inhibition of monocyte TNF-alpha production.Semantic proximity Read ↗

Interleukin-10 and Transforming Growth Factor- β Promoter Polymorphisms in Allergies and AsthmaSemantic proximity Read ↗

Alleles carried at positions -819 and -592 of the IL10 promoter affect transcription following stimulation of peripheral blood cells with Streptococcus pneumoniae.Semantic proximity Read ↗

Detection of polymorphisms within the human IL10 receptor cDNA gene sequence by RT-PCR RFLP.Semantic proximity Read ↗

Chronic obstructive pulmonary disease is associated with the -1055 IL-13 promoter polymorphism.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.