Article
Chronic obstructive pulmonary disease is associated with the -1055 IL-13 promoter polymorphism.
Genes and immunity - 1 Nov 2002
van der Pouw Kraan T C T M, Küçükaycan M, Bakker A M, Baggen J M C, van der Zee J S, Dentener M A, Wouters E F M, Verweij C L
Abstract excerpt
IL-13 is strongly implicated in the development of asthma and chronic obstructive pulmonary disease (COPD). We previously identified an IL-13 promoter polymorphism (-1055 C to T) that is associated with allergic asthma. We now report an increased frequency of the -1055 T allele in COPD patients c...
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