Article
Genome-wide linkage reveals a locus for human essential (primary) hypertension on chromosome 12p.
Human molecular genetics - 1 Jun 2003
Gong Maolian, Zhang Hongye, Schulz Herbert, Lee Young-Ae, Sun Kai, Bähring Sylvia, Luft Friedrich C, Nürnberg Peter, Reis André, Rohde Klaus, Ganten Detlev, Hui Rutai, Hübner Norbert
Abstract excerpt
Essential (primary) hypertension is an important risk factor for cardiovascular morbidity and mortality. Blood pressure is largely heritable; however, the genetic factors contributing to essential hypertension are mostly unknown. We examined a large Chinese kindred (n=387) and selected a subset of 94 individuals for genotyping. An additional 32 Chinese nuclear families with essential hypertension were also...
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