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Article

Polymorphisms of STAT-6, STAT-4 and IFN-gamma genes and the risk of asthma in Chinese population.

Respiratory medicine - 1 Sept 2007

Li Yafei, Wu Bo, Xiong Hongyan, Zhu Caizhong, Zhang Lu

Abstract excerpt

BACKGROUND: Asthma is a complex disease resulting from multiple gene-gene and gene-environment interactions. Study on gene-gene interactions could provide insight into the pathophysiologic mechanisms of the disease. OBJECTIVES: We investigated the single nucleotide polymorphisms and interactions among three different loci in three candidate genes (STAT-6 G2964A, STAT-4 T90089C and IFN-gamma T874A) in 95 Chinese...

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Identifiers

PMID: 17532201
DOI: 10.1016/j.rmed.2007.04.006

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