Article
Dual mechanisms for lysophosphatidic acid stimulation of human ovarian carcinoma cells.
Journal of the National Cancer Institute - 21 May 2003
Hu Yu-Long, Albanese Chris, Pestell Richard G, Jaffe Robert B
Abstract excerpt
BACKGROUND: Lysophosphatidic acid (LPA), at concentrations present in ascitic fluid, indirectly stimulates the growth of malignant ovarian tumors by increasing the expression of vascular endothelial growth factor (VEGF) in ovarian cancer cells. We investigated whether LPA could also directly prom...
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