Article
Mutation of p53 in recurrent hepatocellular carcinoma and its association with the expression of ZBP-89.
The American journal of pathology - 1 Jun 2003
Chen George G, Merchant Juanita L, Lai Paul B S, Ho Rocky L K, Hu Xu, Okada Morihiro, Huang Sheng F, Chui Albert K K, Law David J, Li Yong G, Lau Wan Y, Li Arthur K C
Abstract excerpt
p53 has recently been identified as a downstream target of ZBP-89, a zinc finger transcription factor. ZBP-89 promotes growth arrest through stabilization of the p53 protein. The aim of this study is to determine the status of the p53 gene in recurrent human hepatocellular carcinoma (HCC) and tes...
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