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Article

Role of p53 and β-catenin mutations in conjunction with CK19 expression on early tumor recurrence and prognosis of hepatocellular carcinoma.

Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract - 1 Feb 2011

Yuan Ray-Hwang, Jeng Yung-Ming, Hu Rey-Heng, Lai Po-Lin, Lee Po-Huang, Cheng Chia-Chi, Hsu Hey-Chi

Abstract excerpt

BACKGROUND: Cytokeratin 19 (CK19), a molecular marker of hepatic progenitor cells and cholangiocytes, is expressed in hepatocellular carcinomas (HCC), but not in normal hepatocytes. However, role of CK19 in HCC progression, especially when interacted with p53 and β-catenin mutations, remained largely unknown. MATERIALS AND METHODS: From January 1983 to December 1997, 210 surgically resected, unifocal, primary...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21061181
DOI: 10.1007/s11605-010-1373-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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