Article
Requirement of domain-domain interaction for conformational change and functional ATP hydrolysis in myosin.
The Journal of biological chemistry - 15 Aug 2003
Ito Kohji, Uyeda Taro Q P, Suzuki Yoshikazu, Sutoh Kazuo, Yamamoto Keiichi
Abstract excerpt
Coordination between the nucleotide-binding site and the converter domain of myosin is essential for its ATP-dependent motor activities. To unveil the communication pathway between these two sites, we investigated contact between side chains of Phe-482 in the relay helix and Gly-680 in the SH1-SH...
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