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Article

The two mutations of actin-myosin interface and their effect on the dynamics, structures, and functions of skeletal muscle actin.

Journal of biomolecular structure & dynamics - 1 Feb 2019

Sadat Mohajer Faeze, Parvizpour Sepideh, Razmara Jafar, Shahir Shamsir Mohd

Abstract excerpt

Congenital myopathy is a broad category of muscular diseases with symptoms appearing at the time of birth. One type of congenital myopathy is Congenital Fiber Type Disproportion (CFTD), a severely debilitating disease. The G48D and G48C mutations in the D-loop and the actin-myosin interface are the two causes of CFTD. These mutations have been shown to significantly affect the structure and function of muscle...

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Identifiers

PMID: 29338614
DOI: 10.1080/07391102.2018.1427630

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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