Article
Histocompatibility testing.
The Southeast Asian journal of tropical medicine and public health - 1 Jan 2002
Chee Ren Ee
Abstract excerpt
The human leukocyte antigen (HLA) region on chromosome 6p21.3 is the most polymorphic in the human genome. It encodes hundreds of genes, of which the class I and class II HLA alleles play a central role in the generation of an immune response, but at the same time represent a barrier to marrow and organ transplantation. There is overwhelming evidence that optimal HLA matching will allow for safer marrow...
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