Article
[HLA typing, analysis methods, and clinical applications].
Presse medicale (Paris, France : 1983) - 10 Sept 2005
Moalic V, Ferec C
Abstract excerpt
The polygenic HLA system is a well known region of the human genome. Its main function is to present antigenic peptides to the immune system and thereby regulate induction of immune responses. Extensive genetic polymorphisms characterize some HLA genes. Initially, genetic variations were analyzed by a serological typing technique (microlymphocytotoxicity). The introduction of polymerase chain reaction (PCR) in...
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