Article
[HLA genotyping for molecular epidemiological analysis of humans].
Rinsho byori. The Japanese journal of clinical pathology - 1 Nov 2013
Azuma Fumihiro, Kashiwase Koichi
Abstract excerpt
The major histocompatibility complex (MHC) gene family in humans is termed the human leukocyte antigen (HLA) locus, and is one of the most polymorphic loci in the human genome. HLA and related genes play many important roles in the immune system. HLA matching is critical for the success of organ and hematopoietic stem cell transplantation. Additionally, HLA genes and proteins are associated with autoimmunity,...
Topics
- Genetic Predisposition to Disease
- Genome, Human
- Genotype
- HLA Antigens
- Humans
- Polymorphism, Genetic
- Sequence Analysis, DNA
