Article
Beta-catenin mutations in pulmonary blastomas: association with morule formation.
The Journal of pathology - 1 Jun 2003
Sekine Shigeki, Shibata Tatsuhiro, Matsuno Yoshihiro, Maeshima Arafumi, Ishii Genichiro, Sakamoto Michiie, Hirohashi Setsuo
Abstract excerpt
To elucidate the contribution of beta-catenin gene mutation to the development of pulmonary blastomas, we analysed mutations in three well-differentiated fetal adenocarcinomas (WDFAs) and six biphasic pulmonary blastomas (BPBs). For comparison, eight clear-cell adenocarcinomas with fetal lung features were also examined. beta-Catenin gene mutations were found in all three WDFAs, two BPBs, and none of the...
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