Article
Aberrant nuclear localization and gene mutation of beta-catenin in low-grade adenocarcinoma of fetal lung type: up-regulation of the Wnt signaling pathway may be a common denominator for the development of tumors that form morules.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Jun 2002
Nakatani Yukio, Masudo Katsuhiko, Miyagi Yohei, Inayama Yoshiaki, Kawano Naomi, Tanaka Yukichi, Kato Keisuke, Ito Takaaki, Kitamura Hitoshi, Nagashima Yoji, Yamanaka Shoji, Nakamura Nobuo, Sano Jinyu, Ogawa Nobuo, Ishiwa Naoki, Notohara Kenji, Resl Milan, Mark Eugene J
Abstract excerpt
The salient histopathologic features of low-grade adenocarcinoma of the fetal lung type (L-FLAC)/well-differentiated fetal adenocarcinoma (WDFA) include complex glandular structures and morules with biotin-rich optically clear nuclei. Interestingly, these characteristic features are shared by the cribriform-morular variant of papillary thyroid carcinoma, whose morphology is identical to that of familial...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.