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Article

Distinct properties of pure- and mixed-type high-grade fetal lung adenocarcinomas by genetic profiling and transcription factor expression.

Virchows Archiv : an international journal of pathology - 1 Mar 2022

Kishikawa Satsuki, Hayashi Takuo, Saito Tsuyoshi, Takamochi Kazuya, Sasa Keita, Suehara Yoshiyuki, Takahashi Fumiyuki, Sasahara Noriko, Kohsaka Shinji, Suzuki Kenji, Yao Takashi

Abstract excerpt

The clinicopathological differences among high-grade fetal lung adenocarcinomas completely comprising tumor cells that resemble fetal lung epithelium (pure type) and those with fetal lung-like components admixed with conventional adenocarcinoma cells (mixed type) remain undetermined. Here, we examined the clinicopathological, immunohistochemical, and molecular features of 11 lung adenocarcinomas with fetal...

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Identifiers

PMID: 34846611
DOI: 10.1007/s00428-021-03247-7

Genes

CDX2
CTNNB1
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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