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Article

Expression and mutation analysis of EGFR, c-KIT, and β-catenin in pulmonary blastoma.

Journal of clinical pathology - 1 Apr 2011

Macher-Goeppinger Stephan, Penzel Roland, Roth Wilfried, Dienemann Hendrik, Thomas Michael, Schnabel Philipp Albert, Schirmacher Peter, Bläker Hendrik

Abstract excerpt

INTRODUCTION: Pulmonary blastoma (PB) is a rare malignant lung tumour with an immature mesenchymal and epithelial component resembling fetal lung. In order to define potential therapeutic targets in PB, the authors analysed the status and possible role of EGFR, HER2 and c-KIT in the pathogenesis of this tumour type, and the diagnostic value of β-catenin mutation analysis in PB. METHODS: 5 PBs were analysed for...

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Source

Identifiers

PMID: 21292787
DOI: 10.1136/jcp.2010.085696

Genes

EGFR
KIT
CTNNB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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