Article
Pulmonary blastoma. An immunohistochemical analysis with comparison with fetal lung in its pseudoglandular stage.
American journal of clinical pathology - 1 Feb 1990
Yousem S A, Wick M R, Randhawa P, Manivel J C
Abstract excerpt
Pulmonary blastomas are believed to be mixed epithelial and mesenchymal tumors that recapitulate the developing lung at 10-16 weeks gestation. The authors compared nine blastomas with ten fetal lungs in the pseudoglandular stage of development with a panel of antibodies to various lung antigens to evaluate immunophenotypic homology. Both blastomas and embryonal lungs showed expression of cytokeratin, epithelial...
Topics
- Adult
- Antigens, Neoplasm
- Carcinoembryonic Antigen
- Cytoskeletal Proteins
- Epithelium
- Female
- Fetus
- Humans
- Immunohistochemistry
- Lung
- Lung Neoplasms
- Male
