Article
Amyloid beta-protein stimulates the expression of urokinase-type plasminogen activator (uPA) and its receptor (uPAR) in human cerebrovascular smooth muscle cells.
The Journal of biological chemistry - 23 May 2003
Davis Judianne, Wagner Matthew R, Zhang Weibing, Xu Feng, Van Nostrand William E
Abstract excerpt
The accumulation of fibrillar amyloid-beta protein (A beta) in cerebral blood vessels, a condition known as cerebral amyloid angiopathy (CAA), is a key pathological feature of Alzheimer's disease and certain related disorders and is intimately associated with cerebrovascular cell death both in vi...
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