Article
Genetic evaluation of the TNF-α -238G>A and -308G>A promoter polymorphisms in Croatian patients with type I diabetes.
Human immunology - 1 Dec 2010
Korolija Marina, Hadžija Mirko, Medvidović Edita Pape, Pavkovic Pajica, Kapitanović Sanja, Renar Ivana Pavlić, Hadžija Marijana Popović
Abstract excerpt
A case-control study was performed to establish a potential association of two TNF-α gene promoter SNPs (-238G>A and -308G>A) with occurrence of type 1 Diabetes mellitus (T1DM) in Croatian population (174 patients and 193 healthy controls). Genotypes (obtained by polymerase chain reaction-restriction fragment length polymorphism), and the clinical parameters of T1DM patients were statistically evaluated by SPSS...
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