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Article

The association of TNF-α -308G/A and -238G/A polymorphisms with type 2 diabetes mellitus: a meta-analysis.

Bioscience reports - 20 Dec 2019

Guo Xiaoliang, Li Chenxi, Wu Jiawei, Mei Qingbu, Liu Chang, Sun Wenjing, Xu Lidan, Fu Songbin

Abstract excerpt

Tumor necrosis factor-α (TNF-α) is involved in insulin resistance and has long been a candidate gene implicated in type 2 diabetes mellitus (T2DM), however the association between TNF-α polymorphisms -308G/A and -238G/A and T2DM remains controversial. The present study sought to verify associations between these polymorphisms and T2DM susceptibility using a meta-analysis approach. A total of 49 case-control...

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Identifiers

PMID: 31803921
DOI: 10.1042/BSR20191301
PMCID: PMC6923338

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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