Article
Regulation of gene transcription by a constitutively active mutant of activating transcription factor 2 (ATF2).
Biological chemistry - 1 Apr 2003
Steinmüller Lars, Thiel Gerald
Abstract excerpt
Activating transcription factor 2 (ATF2) belongs to the family of basic region leucine zipper (bZIP) proteins that are characterized by the presence of a basic domain that functions as the DNA-binding domain and a leucine zipper domain that is required for dimerization. Together with bZIP proteins of the Fos and Jun families, ATF2 constitutes the AP-1 transcription factor complex. The biological activity of ATF2...
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