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Article

A mutant TP53 gene status is associated with a poor prognosis and anthracycline-resistance in breast cancer patients.

European journal of cancer (Oxford, England : 1990) - 1 Mar 2003

Rahko E, Blanco G, Soini Y, Bloigu R, Jukkola A

Abstract excerpt

This study evaluates the prognostic and predictive relevance of a mutated p53 in a series of 254 samples from primary breast cancer patients. C-erbB-2 analysis was defined in a limited subpopulation of 79 patients. p53 and c-erbB-2 status was analysed by immunohistochemical staining of the tumour samples. Positive p53 immunostaining was present in 86 cases (34%) and correlated with a high malignant grade,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12751374
DOI: 10.1016/s0959-8049(02)00499-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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