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Article

Association of positional and functional candidate genes FGF1, FBN2, and LOX on 5q31 with intracranial aneurysm.

Journal of human genetics - 1 Jan 2003

Yoneyama Taku, Kasuya Hidetoshi, Onda Hideaki, Akagawa Hiroyuki, Jinnai Nobuyoshi, Nakajima Toshiaki, Hori Tomokatsu, Inoue Ituro

Abstract excerpt

We previously performed a genome-wide linkage study of intracranial aneurysm (IA) and found positive evidence of linkage at chromosomes 5q22-31, 7q11, and 14q22. In the present study, we focus on 5q31, where three candidate genes, fibroblast growth factor 1 (FGF1), fibrillin 2 (FBN2), and lysyl oxidase gene ( LOX) lie, and evaluate associations with IA. Genomic DNAs were obtained from 172 IA patients and 192...

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Identifiers

PMID: 12750963
DOI: 10.1007/s10038-003-0030-6

Genes

FGF1
FBN2
LOX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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