Article
Polymorphisms in Lysyl Oxidase Family Genes Are Associated With Intracranial Aneurysm Susceptibility in a Chinese Population.
Frontiers in endocrinology - 1 Jan 2021
Luo Chun, Hu Chongyu, Li Bingyang, Liu Junyu, Hu Liming, Dong Rui, Liao Xin, Zhou Jilin, Xu Lu, Liu Songlin, Li Yifeng, Yuan Dun, Jiang Weixi, Yan Junxia
Abstract excerpt
Purpose: Intracranial aneurysms (IA) comprise a multifactorial disease with unclear physiological mechanisms. The lysyl oxidase (LOX) family genes (LOX, LOX-like 1-4) plays important roles in extracellular matrix (ECM) reconstruction and has been investigated in terms of susceptibility to IA in a few populations. We aimed to determine whether polymorphisms in LOX family genes are associated with susceptibility to...
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