Article
Association study of the vitamin D: 1alpha-hydroxylase (CYP1alpha) gene and type 2 diabetes mellitus in a Polish population.
Diabetes & metabolism - 1 Apr 2003
Malecki M T, Klupa T, Wolkow P, Bochenski J, Wanic K, Sieradzki J
Abstract excerpt
OBJECTIVES: Type 2 diabetes mellitus (T2DM) is a complex disease. Genetic and environmental factors cooperate together to form its clinical picture. Polymorphisms in genes involved in the metabolism of vitamin D may influence susceptibility to T2DM. One of them is the vitamin D 1alpha-hydroxylase (CYP1alpha) gene. In this study we searched for the association of two markers, one in its intron 6 and the another...
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