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Article

Vitamin D 1alpha-hydroxylase (CYP1alpha) polymorphism in Graves' disease, Hashimoto's thyroiditis and type 1 diabetes mellitus.

European journal of endocrinology - 1 Jun 2002

Pani Michael A, Regulla Karoline, Segni Maria, Krause Maren, Hofmann Stefan, Hufner Michael, Herwig Jurgen, Pasquino Anna Maria, Usadel Klaus-H, Badenhoop Klaus

Abstract excerpt

OBJECTIVE: The vitamin D endocrine system plays a role in the regulation of (auto)immunity and cell proliferation. Vitamin D 1alpha-hydroxylase (CYP1alpha) is one of the key enzymes regulating both systemic and tissue levels of 1,25-dihyroxyvitamin D(3) (1,25(OH)(2)D(3)). Administration of 1,25(OH)(2)D(3), whose serum levels were found to be reduced in type 1 diabetes and thyroid autoimmunity, prevents these...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 1

Share to Gene Expression Regulation, Enzymologic

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Share to HLA-DQ Antigens

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Source

Identifiers

PMID: 12039697
DOI: 10.1530/eje.0.1460777

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Vitamin D 1alpha-hydroxylase (CYP1alpha) polymorphism in Graves' disease, Hashimoto's thyroiditis and type 1 diabetes mellitus.PMID 12039697Read ↗

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