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Article

Association of the vitamin D metabolism gene CYP27B1 with type 1 diabetes.

Diabetes - 1 Oct 2007

Bailey Rebecca, Cooper Jason D, Zeitels Lauren, Smyth Deborah J, Yang Jennie H M, Walker Neil M, Hyppönen Elina, Dunger David B, Ramos-Lopez Elizabeth, Badenhoop Klaus, Nejentsev Sergey, Todd John A

Abstract excerpt

OBJECTIVE: Epidemiological studies have linked vitamin D deficiency with the susceptibility to type 1 diabetes. Higher levels of the active metabolite 1 alpha,25-dihydroxyvitamin D (1 alpha,25(OH)(2)D) could protect from immune destruction of the pancreatic beta-cells. 1 alpha,25(OH)(2)D is derived from its precursor 25-hydroxyvitamin D by the enzyme 1 alpha-hydroxylase encoded by the CYP27B1 gene and is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17606874
DOI: 10.2337/db07-0652
PMCID: PMC2493063

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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