Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Unexpected roles of a Dictyostelium homologue of eukaryotic EF-2 in growth and differentiation.

Journal of cell science - 1 Jul 2003

Watanabe Sohsuke, Sakurai Kohji, Amagai Aiko, Maeda Yasuo

Abstract excerpt

EF-2 is believed to be indispensable for polypeptide chain elongation in protein synthesis and therefore for cell proliferation. Surprisingly, we could isolate ef2 null cells from Dictyostelium discoideum that exhibited almost normal growth and protein synthesis, which suggests that there is another molecule capable of compensating for EF-2 function. The knock-out of Dictyostelium EF-2 (Dd-EF2H; 101 kDa...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Aggregation
Share to Cell Division
Share to Cell Nucleus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dictyostelium

Share to Giant Cells

Share to Mitochondria

Share to Sequence Homology, Amino Acid

Share to Sequence Homology, Nucleic Acid

Source

Identifiers

PMID: 12746492
DOI: 10.1242/jcs.00476

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Unexpected roles of a Dictyostelium homologue of eukaryotic EF-2 in growth and differentiation.PMID 12746492Read ↗

Dictyostelium discoideum as a Model for Investigating Neurodegenerative DiseasesSemantic proximity Read ↗

Identification of proteins involved in cytokinesis of Dictyostelium.Semantic proximity Read ↗

Dictyostelium discoideum as a non‐mammalian biomedical modelSemantic proximity Read ↗

Gdt2 regulates the transition of Dictyostelium cells from growth to differentiation.Semantic proximity Read ↗

A Phg2-Adrm1 pathway participates in the nutrient-controlled developmental response in Dictyostelium.Semantic proximity Read ↗

Ndufaf5 deficiency in the Dictyostelium model: new roles in autophagy and development.Semantic proximity Read ↗

Mef2A, a homologue of animal Mef2 transcription factors, regulates cell differentiation in Dictyostelium discoideum.Semantic proximity Read ↗

A novel role of differentiation-inducing factor-1 in Dictyostelium development, assessed by the restoration of a developmental defect in a mutant lacking mitogen-activated protein kinase ERK2.Semantic proximity Read ↗

Dd-STATb, a Dictyostelium STAT protein with a highly aberrant SH2 domain, functions as a regulator of gene expression during growth and early development.Semantic proximity Read ↗

Isolation of Dictyostelium discoideum cytokinesis mutants by restriction enzyme-mediated integration of the blasticidin S resistance marker.Semantic proximity Read ↗

Calcium regulation of actin crosslinking is important for function of the actin cytoskeleton in Dictyostelium.Semantic proximity Read ↗

Isolation and characterization of a novel cytokinesis-deficient mutant in Dictyostelium discoideum.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.