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Article

Cytochrome P450 genes are differentially expressed in female and male hepatocyte retinoid X receptor alpha-deficient mice.

Endocrinology - 1 Jun 2003

Cai Yan, Dai Tiane, Ao Yan, Konishi Tamiko, Chuang Kuang-Hsiang, Lue Yanhe, Chang Chawnshang, Wan Yu-Jui Yvonne

Abstract excerpt

To study the functional role of retinoid X receptor alpha (RXRalpha) in hepatocytes, hepatocyte RXRalpha-deficient mice have been established. Characterization has been performed on male mice. In this paper, we show that the expression of CYP450 genes is differentially expressed in male and female hepatocyte RXRalpha-deficient mice; male mice have reduced expression of cytochrome P450 (CYP) CYP4A, CYP3A, and...

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Identifiers

PMID: 12746291
DOI: 10.1210/en.2002-0129

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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