Article
Functional conservation and divergence of intersex, a gene required for female differentiation in Drosophila melanogaster.
Development genes and evolution - 1 Jan 2005
Siegal Mark L, Baker Bruce S
Abstract excerpt
In Drosophila melanogaster, somatic sexual differentiation is regulated by a well characterized genetic hierarchy, by which the ratio of X chromosomes to autosomes (X:A) ultimately directs the deployment of sex-specific transcription factors encoded by doublesex (dsx) and fruitless (fru). In other dipterans, the X:A ratio is not the primary sex-determination signal. Correspondingly, the Drosophila hierarchy is...
Topics
- Amino Acid Sequence
- Animals
- Animals, Genetically Modified
- Biological Evolution
- Conserved Sequence
- DNA-Binding Proteins
- Databases, Genetic
- Drosophila Proteins
- Drosophila melanogaster
- Female
- Gene Expression Regulation, Developmental
- Insect Proteins
- Male
- Molecular Sequence Data