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Article

Mutations in the glucokinase regulatory protein gene in 2p23 in obese French caucasians.

Diabetologia - 1 May 2003

Veiga-da-Cunha M, Delplanque J, Gillain A, Bonthron D T, Boutin P, Van Schaftingen E, Froguel P

Abstract excerpt

AIMS/HYPOTHESIS: Glucokinase regulatory protein (GKRP) controls the activity of glucokinase in liver but possibly also in some areas of the central nervous system, suggesting that it could play a role in body mass control. Its gene is located in a region (2p21-23) linked to serum leptin levels. Our goal was to investigate whether mutations in the GKRP gene were associated with obesity. METHODS: Mutations were...

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Identifiers

PMID: 12739015
DOI: 10.1007/s00125-003-1083-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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