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Article

Analysis of PINCH function in Drosophila demonstrates its requirement in integrin-dependent cellular processes.

Development (Cambridge, England) - 1 Jun 2003

Clark Kathleen A, McGrail Maura, Beckerle Mary C

Abstract excerpt

Integrins play a crucial role in cell motility, cell proliferation and cell survival. The evolutionarily conserved LIM protein PINCH is postulated to act as part of an integrin-dependent signaling complex. In order to evaluate the role of PINCH in integrin-mediated cellular events, we have tested directly the in vivo function of PINCH in Drosophila melanogaster. We demonstrate that the steamer duck (stck) alleles...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12736206
DOI: 10.1242/dev.00492

Genes

ILK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Analysis of PINCH function in Drosophila demonstrates its requirement in integrin-dependent cellular processes.PMID 12736206Read ↗

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