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Article

Cellular responses to Sindbis virus infection of neural progenitors derived from human embryonic stem cells.

BMC research notes - 24 Oct 2014

Xu Jie, Nash Rodney J, Frey Teryl K

Abstract excerpt

BACKGROUND: Sindbis virus (SINV) causes age-dependent encephalitis in mice, and therefore serves as a model to study viral encephalitis. SINV is used as a vector for the delivery of genes into selected neural stem cell lines; however, the toxicity and side effects of this vector have rarely been discussed. In this context, we investigated the cellular responses of human embryonic stem cell (hESCs) derived neural...

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Identifiers

PMID: 25343994
DOI: 10.1186/1756-0500-7-757
PMCID: PMC4307679

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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