Article
Cytokines regulate the cellular phenotype of developing neural lineage species.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience - 1 Jan 2000
Mehler M F, Marmur R, Gross R, Mabie P C, Zang Z, Papavasiliou A, Kessler J A
Abstract excerpt
The patterns and mechanisms of action of inductive signals that orchestrate neural lineage commitment and differentiation in the mammalian brain are incompletely understood. To examine these developmental issues, we have utilized several culture systems including conditionally immortalized cell lines, subventricular zone progenitor cells and primary neuronal cultures. A neural stem and progenitor cell line (MK31)...
Topics
- Animals
- Antimetabolites
- Base Sequence
- Blotting, Southern
- Brain
- Bromodeoxyuridine
- Cell Lineage
- Coloring Agents
- Cytokines
- Humans
- Immunohistochemistry
