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Article

The generation of neurons and oligodendrocytes from a common precursor cell.

Neuron - 1 Oct 1991

Williams B P, Read J, Price J

Abstract excerpt

We have used a recombinant retrovirus carrying the lacZ gene to study the developmental potential of precursor cells from the embryonic rat cerebral cortex in dissociated cell culture. Virus was used to label a small number of cultured cells genetically so that their fate could be determined. Infected clones were detected with an anti-beta-galactosidase serum, and the labeled cells were identified using...

Topics

Animals
Cell Line
Cerebral Cortex
Clone Cells
Genetic Markers
Immunohistochemistry
Neurons
Oligodendroglia
Phenotype
Recombination, Genetic
Retroviridae
Stem Cells

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Source

Identifiers

PMID: 1931054
DOI: 10.1016/0896-6273(91)90381-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1931054-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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