Article
Genomic Epidemiology and Molecular Resistance Mechanisms of Azithromycin-Resistant Neisseria gonorrhoeae in Canada from 1997 to 2014.
Journal of clinical microbiology - 1 May 2016
Demczuk Walter, Martin Irene, Peterson Shelley, Bharat Amrita, Van Domselaar Gary, Graham Morag, Lefebvre Brigitte, Allen Vanessa, Hoang Linda, Tyrrell Greg, Horsman Greg, Wylie John, Haldane David, Archibald Chris, Wong Tom, Unemo Magnus, Mulvey Michael R
Abstract excerpt
The emergence of Neisseria gonorrhoeae strains with decreased susceptibility to cephalosporins and azithromycin (AZM) resistance (AZM(r)) represents a public health threat of untreatable gonorrhea infections. Genomic epidemiology through whole-genome sequencing was used to describe the emergence, dissemination, and spread of AZM(r) strains. The genomes of 213 AZM(r) and 23 AZM-susceptible N. gonorrhoeae isolates...
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