Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Impact of mutations in the mtrR, rpdlVD and rrl genes on azithromycin resistance in Neisseria gonorrhoeae.

PloS one - 1 Jan 2024

Mauffrey Florian, Poncet Fabrice, Jacot Damien, Greub Gilbert, Nordmann Patrice, Blanc Dominique S

Abstract excerpt

INTRODUCTION: Bacterial sexually transmitted infections (STIs) pose a major public health problem. The emergence of antibiotic-resistant strains of Neisseria gonorrhoeae represents a serious threat to successful treatment and epidemiological control. The first extensively drug-resistant (XDR) strains (ceftriaxone-resistant and high-level azithromycin-resistant [HLR AZY]) have been reported. AIMS: To identify...

Topics

Join the communities discussing this publication.

Anti-Bacterial Agents
Azithromycin
Drug Resistance, Bacterial
Gonorrhea
Microbial Sensitivity Tests

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neisseria gonorrhoeae

Repressor Proteins

Ribosomal Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 39012901
DOI: 10.1371/journal.pone.0306695
PMCID: PMC11251580

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Impact of mutations in the mtrR, rpdlVD and rrl genes on azithromycin resistance in Neisseria gonorrhoeae.PMID 39012901Read ↗

Molecular pathways to high-level azithromycin resistance in Neisseria gonorrhoeae.Semantic proximity Read ↗

WGS analysis and molecular resistance mechanisms of azithromycin-resistant (MIC >2 mg/L) Neisseria gonorrhoeae isolates in Europe from 2009 to 2014.Semantic proximity Read ↗

Molecular epidemiology and mechanisms of resistance of azithromycin-resistant Neisseria gonorrhoeae isolated in France during 2013-14.Semantic proximity Read ↗

Azithromycin susceptibility of Neisseria gonorrhoeae in the USA in 2017: a genomic analysis of surveillance dataSemantic proximity Read ↗

Emergence of High-Level Azithromycin Resistance in Neisseria gonorrhoeae : Genomic Insights From a 9-Year (2016-2024) Study From North India.Semantic proximity Read ↗

Genomic Epidemiology and Molecular Resistance Mechanisms of Azithromycin-Resistant Neisseria gonorrhoeae in Canada from 1997 to 2014.Semantic proximity Read ↗

Phenotypic and genotypic characterization of Neisseria gonorrhoeae isolates among individuals at high risk for sexually transmitted diseases in Zurich, Switzerland.Semantic proximity Read ↗

Decreased Azithromycin Susceptibility ofNeisseria gonorrhoeaeIsolates in Patients Recently Treated with AzithromycinSemantic proximity Read ↗

Characterization of a novel mosaic-like mtr operon and inter-regional transmission of dual-resistant Neisseria gonorrhoeae ST7363 sub-lineage in China.Semantic proximity Read ↗

Azithromycin-resistant Neisseria gonorrhoeae spreading amongst men who have sex with men (MSM) and heterosexuals in New South Wales, Australia, 2017.Semantic proximity Read ↗

The Mosaic mtr Locus as Major Genetic Determinant of Azithromycin Resistance of Neisseria gonorrhoeae—Germany, 2018Semantic proximity Read ↗

Using genomics to understand antimicrobial resistance and transmission in Neisseria gonorrhoeaeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.